IKZF2 anticorps (AA 51-107) (PE)

N° du produit ABIN5541431

Cet anticorps Hamster Monoclonal détecte spécifiquement IKZF2 dans FACS. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour IKZF2 anticorps (AA 51-107) (PE) (ABIN5541431)

Antigène: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Reactivité: Humain, Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp IKZF2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 22F6

Détail du produit anti-IKZF2 anticorps (PE)

Épitope: AA 51-107

Specificité: This antibody recognizes Helios, a transcription factor expressed in some hematopoietic stem cells, and at high levels in thymic-derived regulatory T cells.

Immunogène: Peptide coresponding to the amino acids 51-107 of Helios

Isotype: IgG

Information d'application

Indications d'application: Flow cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10 6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IKZF2

Antigène: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Autre désignation: znfn1a2 (ikzf2, helios)

Sujet: Helios, also known as IKZF2 (Ikaros family zinc finger protein 2) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Ikaros. Helios forms homo- and heterodimers with these proteins and is thought to function predominantly in early hematopoietic development. Expression of Helios, Aiolos and Ikaros is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Helios is expressed at early stages of thymocyte development. In mature T cells, Helios has been strongly associated with Treg cells.

UniProt: Q9UKS7