Rituximab anticorps (HRP)

N° du produit ABIN5541687

L’anticorps Rat Monoclonal anti-Rituximab a été validé pour EIA. Il convient pour détecter Rituximab dans des échantillons de .

Aperçu rapide pour Rituximab anticorps (HRP) (ABIN5541687)

Antigène: Rituximab

Reactivité: Veuillez nous consulter SVP

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Rituximab est conjugé à/à la HRP

Application: Enzyme Immunoassay (EIA)

Clone: MB2 A4

Détail du produit anti-Rituximab anticorps (HRP)

Specificité: This antibody specifically recognises the idiotypic determinants expressed by the Rituximab humanised monoclonal antibody. This antibody does not recognise other CD20 antibodies. It has been used to detect Rituximab bound to the surface of the Raji B cell line, however detection of Rituximab bound 'in vivo' to B-CLL cells has not been demonstrated. It is possible that complement deposition on Rituximab opsonised cells inhibits binding of the anti-Rituximab antibody to cell bound Rituximab (3). Clone MB2A4 has been used in ELISA assays to monitor the levels of rituximab in patient serum following therapy (4,5).

Purification: Affinity chromatography on Protein G

Immunogène: F(ab)2 fragment of Rituximab

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: 1/20000-1/20000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C

Stockage commentaire: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Rituximab

Antigène: Rituximab

Classe de substances: Antibody

Sujet: Rituximab is a therapeutic reagent directed against the human CD20 cell surface antigen.