LRRC32 anticorps

N° du produit ABIN5541855

L’anticorps anti-LRRC32 Monoclonal produit chez le Souris a été validé pour WB, FACS, IP et EIA. Il convient pour la détection de LRRC32 dans des échantillons provenant de Humain. }

Aperçu rapide pour LRRC32 anticorps (ABIN5541855)

Antigène: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LRRC32 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Clone: GARP5

Détail du produit anti-LRRC32 anticorps

Specificité: This antibody recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.

Purification: Protein-A affinity chromatography

Immunogène: Purified human sGARP protein

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry. Immunoprecipitation. Western blot. ELISA.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur LRRC32

Antigène: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Autre désignation: lrrc32,garp

Sujet: GARP (glycoprotein A repetitions predominant protein), also known as Garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.

UniProt: Q14392

Pathways: Activated T Cell Proliferation