GNRH1 anticorps (AA 11-60)

N° du produit ABIN5541891

L’anticorps anti-GNRH1 Polyclonal Lapin est utilisé pour la détection de GNRH1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et IHC (p).

Aperçu rapide pour GNRH1 anticorps (AA 11-60) (ABIN5541891)

Antigène: GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNRH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GNRH1 anticorps

Épitope: AA 11-60

Specificité: This antibody detects endogenous levels of GnRH 1 protein.

Purification: Affinity Chromatography using epitope-specific immunogen

Immunogène: Synthetic peptide corresponding to amino acids 11-60 of Human GnRH I.

Information d'application

Indications d'application: Western blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 95 % by SDS-PAGE) Aff - Purified

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur GNRH1

Antigène: GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))

Autre désignation: gnrh1,progonadoliberin-1

Sujet: GnRH is produced by hypothalamic neurons and secreted in a pulsatile manner into the capillary plexus of the median eminence. GnRH affects the release of lutenizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary. In addition to hypothalamic GnRH (GnRH I), a second GnRH form (GnRH II) functions primarily in the midbrain. GnRH is xpressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells. Unlike GnRH I, GnRH II is highly expressed outside the brain, particularly in the kidney, bone marrow and prostate, suggesting that it may have multiple functions. GnRH binds to a specific G protein-coupled receptor in the pituitary to regulate synthesis and secretion of gonadotropins.

UniProt: P01148

Pathways: Hormone Activity