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GZMK anticorps

GZMK Reactivité: Humain FACS, EIA Hôte: Souris Monoclonal GM24C3 unconjugated
N° du produit ABIN5541917
  • Antigène Voir toutes GZMK Anticorps
    GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))
    Reactivité
    • 50
    • 22
    • 17
    • 3
    • 1
    Humain
    Hôte
    • 46
    • 8
    Souris
    Clonalité
    • 48
    • 6
    Monoclonal
    Conjugué
    • 26
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GZMK est non-conjugé
    Application
    • 40
    • 18
    • 16
    • 12
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Specificité
    This antibody recognizes Granzyme K (GZMK). Species: Human.
    Purification
    Affinity Chromatography on Protein G
    Immunogène
    GM24C3 was generated by genetic immunisation of BALB/c mice with an immunisation vector containing the Granzyme K cDNA
    Clone
    GM24C3
    Isotype
    IgG2b
    Top Product
    Discover our top product GZMK Anticorps primaire
  • Indications d'application
    Flow Cytometry: 1.2 μg/10 6 cells. ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.2 without preservatives
    Agent conservateur
    Without preservative
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
    Date de péremption
    12 months
  • Krause, Behrends, Borowski, Lohrmann, Lang, Myrtek, Lorenzen, Virchow, Luttmann, Friedrich: "Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor alpha1." dans: Molecular immunology, Vol. 43, Issue 11, pp. 1799-807, (2006) (PubMed).

    Bratke, Kuepper, Bade, Virchow, Luttmann: "Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood." dans: European journal of immunology, Vol. 35, Issue 9, pp. 2608-16, (2005) (PubMed).

  • Antigène
    GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))
    Autre désignation
    granzyme k (gzmk) (GZMK Produits)
    Synonymes
    anticorps TRYP2, anticorps granzyme K, anticorps GZMK, anticorps Gzmk
    Sujet
    Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
    UniProt
    P49863
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