GZMK anticorps

N° du produit ABIN5541918

L’anticorps Souris Monoclonal anti-GZMK a été validé pour FACS, EIA et ELISA (Capture). Il convient pour détecter GZMK dans des échantillons de Humain.

Aperçu rapide pour GZMK anticorps (ABIN5541918)

Antigène: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMK est non-conjugé

Application: Flow Cytometry (FACS), Enzyme Immunoassay (EIA), ELISA (Capture)

Clone: GM26E7

Détail du produit anti-GZMK anticorps

Specificité: This antibody reacts to Granzyme K (GZMK). Species: Human.

Purification: Affinity Chromatography on Protein G

Immunogène: Genetic immunisation with cDNA encoding human Granzyme K

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: 1.2 μg/10 6 cells. ELISA: 1/200-1/400. ELISA (capture): Clone GM-6C3 as detection antibody. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2

Stock: 4 °C,-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur GZMK

Antigène: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Autre désignation: granzyme k (gzmk)

Sujet: Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.

UniProt: P49863