CD27 anticorps

N° du produit ABIN5541980

Cet anticorps Hamster Monoclonal détecte spécifiquement CD27 dans FACS, IHC (p), IHC (fro) et Func. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour CD27 anticorps (ABIN5541980)

Antigène: CD27 (CD27 Molecule (CD27))

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD27 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: LG-3A10

Détail du produit anti-CD27 anticorps

Specificité: Recognizes Mouse CD27 receptor.

Purification: Protein G Chromatography

Immunogène: MCD27 tag expressing clones AR0524 and AR0530 from Armenian Hamster spleen.

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: Functional Studies (stimulating). Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: This clone (LG.3A10) has been reported to work on Paraffin tissue sections.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS Preservatives: None

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD27

Antigène: CD27 (CD27 Molecule (CD27))

Autre désignation: cd27

Sujet: CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both αβ and γδ T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8- precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events.

UniProt: P41272

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints