CD46 anticorps (AA 35-313)

N° du produit ABIN5541991

Cet anticorps anti-CD46 est un anticorps Souris Monoclonal détectant CD46 dans WB et EIA. Adapté pour Humain.

Aperçu rapide pour CD46 anticorps (AA 35-313) (ABIN5541991)

Antigène: CD46

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT2G9

Détail du produit anti-CD46 anticorps

Épitope: AA 35-313

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human CD46 (35-313aa) purified from E. coli.

Isotype: IgG2a

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD46

Antigène: CD46

Autre désignation: cd46,mcp

Sujet: Membrane Cofactor Protein (CD46) is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. This protein is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is implicated in the development and/or progression of selected cancer types.

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization