MMP17 anticorps

N° du produit ABIN5542064

Cet anticorps Souris Monoclonal détecte spécifiquement MMP17 dans EIA et Neut. Il présente une réactivité envers Humain.

Aperçu rapide pour MMP17 anticorps (ABIN5542064)

Antigène: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP17 est non-conjugé

Application: Enzyme Immunoassay (EIA), Neutralization (Neut)

Clone: 12N24

Détail du produit anti-MMP17 anticorps

Specificité: This antibody recognizes Human MMP-17 by direct ELISA.

Purification: Protein G Chromatography

Immunogène: Recombinant Human MMP-17

Isotype: IgG2

Information d'application

Indications d'application: ELISA: 1/1000-1/2000. Neutralization.

Restrictions: For Research Use only

Stockage

Buffer: Sterile PBS

Stock: 4 °C,-20 °C

Stockage commentaire: Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur MMP17

Antigène: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Autre désignation: mmp-17

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage and is known to be expressed in brain, leukocytes, colon, ovary testis and breast cancer as well as in many transformed and non-transformed cell types. The protein exists in two isoforms: a GPI-anchored form and a second secreted form.

UniProt: Q9ULZ9