SNAIL anticorps (AA 1-264)

N° du produit ABIN5542116

L’anticorps Souris Monoclonal anti-SNAIL a été validé pour WB et EIA. Il convient pour détecter SNAIL dans des échantillons de Humain.

Aperçu rapide pour SNAIL anticorps (AA 1-264) (ABIN5542116)

Antigène: SNAIL (SNAI1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SNAIL est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT2D5

Détail du produit anti-SNAIL anticorps

Épitope: AA 1-264

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human SNAI1 (1-264aa) purified from E. coli

Isotype: IgG2b

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.Recommended starting dilution is 1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur SNAIL

Antigène: SNAIL (SNAI1)

Autre désignation: snai1

Sujet: SNAI1, also known as Snail homolog 1, is involved in the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. This protein binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. Both SNAI1 and SLUG belong to the snail C2H2-type zinc-finger protein family. SLUG is a transcriptional repressor, involved in the generation and migration of neural crest cells. SNAI1 is expressed in mesenchymal, epithelial cell lines and highest expression in kidney.

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling