PKN1 anticorps (AA 442-620)
Aperçu rapide pour PKN1 anticorps (AA 442-620) (ABIN5542353)
Antigène
Voir toutes PKN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 442-620
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Fonction
- PKN1 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human PKN1 (AA: 442-620) expressed in E. Coli.
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Isotype
- IgG2b
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PKN1 (Protein Kinase N1 (PKN1))
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Autre désignation
- PKN1
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Sujet
- The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
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Poids moléculaire
- 104 kDa
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ID gène
- 5585
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UniProt
- Q16512
Antigène
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