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PKN1 anticorps (AA 442-620)

L’anticorps Souris Monoclonal anti-PKN1 a été validé pour ELISA, IHC, ICC et FACS. Il convient pour détecter PKN1 dans des échantillons de Humain.
N° du produit ABIN5542353

Aperçu rapide pour PKN1 anticorps (AA 442-620) (ABIN5542353)

Antigène

Voir toutes PKN1 Anticorps
PKN1 (Protein Kinase N1 (PKN1))

Reactivité

  • 34
  • 8
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 22
  • 12
Souris

Clonalité

  • 23
  • 11
Monoclonal

Conjugué

  • 20
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Cet anticorp PKN1 est non-conjugé

Application

  • 20
  • 6
  • 5
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone

4H10B1
  • Épitope

    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 442-620

    Fonction

    PKN1 Antibody

    Purification

    Purified antibody

    Immunogène

    Purified recombinant fragment of human PKN1 (AA: 442-620) expressed in E. Coli.

    Isotype

    IgG2b
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified antibody in PBS with 0.05 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène

    PKN1 (Protein Kinase N1 (PKN1))

    Autre désignation

    PKN1

    Sujet

    The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

    Poids moléculaire

    104 kDa

    ID gène

    5585

    UniProt

    Q16512
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