UFD1L anticorps (AA 208-307)
Aperçu rapide pour UFD1L anticorps (AA 208-307) (ABIN5542400)
Antigène
Voir toutes UFD1L AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 208-307
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Fonction
- UFD1L Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human UFD1L (AA: 208-307) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
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Autre désignation
- UFD1L
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Sujet
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The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
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Poids moléculaire
- 34.5 kDa
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ID gène
- 7353
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UniProt
- Q92890
Antigène
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