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MECP2 anticorps (AA 7-148)

Cet anticorps Souris Monoclonal détecte spécifiquement MECP2 dans WB, ELISA, IHC, FACS et ICC. Il présente une réactivité envers Humain.
N° du produit ABIN5542475

Aperçu rapide pour MECP2 anticorps (AA 7-148) (ABIN5542475)

Antigène

Voir toutes MECP2 Anticorps
MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Reactivité

  • 103
  • 41
  • 31
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Humain

Hôte

  • 101
  • 9
  • 1
Souris

Clonalité

  • 102
  • 9
Monoclonal

Conjugué

  • 70
  • 9
  • 7
  • 7
  • 6
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MECP2 est non-conjugé

Application

  • 81
  • 62
  • 38
  • 25
  • 12
  • 11
  • 10
  • 8
  • 6
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone

8H4A5B9
  • Épitope

    • 14
    • 11
    • 11
    • 8
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 7-148

    Fonction

    MECP2 Antibody

    Purification

    Purified antibody

    Immunogène

    Purified recombinant fragment of human MECP2 (AA: 7-148) expressed in E. Coli.

    Isotype

    IgG1
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified antibody in PBS with 0.05 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Antigène

    MECP2 (Methyl CpG Binding Protein 2 (MECP2))

    Autre désignation

    MECP2

    Sujet

    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.

    Poids moléculaire

    52.4 kDa

    UniProt

    P51608

    Pathways

    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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