RAP1GAP anticorps (AA 412-660)

N° du produit ABIN5542476

L’anticorps Souris Monoclonal anti-RAP1GAP a été validé pour ELISA et FACS. Il convient pour détecter RAP1GAP dans des échantillons de Humain.

Aperçu rapide pour RAP1GAP anticorps (AA 412-660) (ABIN5542476)

Antigène: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RAP1GAP est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 2G7B6

Détail du produit anti-RAP1GAP anticorps

Épitope: AA 412-660

Fonction: RAP1GAP Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human RAP1GAP (AA: 412-660) expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur RAP1GAP

Antigène: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Autre désignation: RAP1GAP

Sujet: This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Poids moléculaire: 73.4 kDa

UniProt: P47736