LRP1 anticorps (AA 20-155)
Aperçu rapide pour LRP1 anticorps (AA 20-155) (ABIN5542496)
Antigène
Voir toutes LRP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 20-155
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Fonction
- LRP1 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human LRP1 (AA: 20-155) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
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Autre désignation
- LRP1
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Sujet
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The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.
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Poids moléculaire
- 50.5 kDa
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UniProt
- Q07954
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Pathways
- Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
Antigène
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