DNMT3L anticorps (AA 147-386)

N° du produit ABIN5542515

L’anticorps Souris Monoclonal anti-DNMT3L a été validé pour ELISA et FACS. Il convient pour détecter DNMT3L dans des échantillons de Humain.

Aperçu rapide pour DNMT3L anticorps (AA 147-386) (ABIN5542515)

Antigène: DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DNMT3L est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 2D10H11

Détail du produit anti-DNMT3L anticorps

Épitope: AA 147-386

Fonction: DNMT3L Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human DNMT3L (AA: 147-386) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur DNMT3L

Antigène: DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))

Autre désignation: DNMT3L

Sujet: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 43.6 kDa

ID gène: 29947

UniProt: Q9UJW3