DOC2A anticorps (AA 652-749)

N° du produit ABIN5542714

Cet anticorps anti-DOC2A est un anticorps Souris Monoclonal détectant DOC2A dans ELISA, FACS et ICC. Adapté pour Humain.

Aperçu rapide pour DOC2A anticorps (AA 652-749) (ABIN5542714)

Antigène: DOC2A (Double C2-Like Domains, alpha (DOC2A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DOC2A est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 2H7C4

Détail du produit anti-DOC2A anticorps

Épitope: AA 652-749

Fonction: DOC2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human DOC2 (AA: 652-749) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur DOC2A

Antigène: DOC2A (Double C2-Like Domains, alpha (DOC2A))

Autre désignation: DOC2

Sujet: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 82.4 kDa

UniProt: P98082

Pathways: Synaptic Vesicle Exocytosis