Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

DOC2A anticorps (AA 652-749)

DOC2A Reactivité: Humain WB, ELISA, IHC, FACS, ICC Hôte: Souris Monoclonal 2H7C4 unconjugated
N° du produit ABIN5542714
  • Antigène Voir toutes DOC2A Anticorps
    DOC2A (Double C2-Like Domains, alpha (DOC2A))
    Épitope
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 652-749
    Reactivité
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 17
    • 3
    • 2
    • 1
    Souris
    Clonalité
    • 21
    • 2
    Monoclonal
    Conjugué
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp DOC2A est non-conjugé
    Application
    • 20
    • 16
    • 13
    • 12
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human DOC2 (AA: 652-749) expressed in E. coli.
    Clone
    2H7C4
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    DOC2A (Double C2-Like Domains, alpha (DOC2A))
    Autre désignation
    DOC2 (DOC2A Produits)
    Synonymes
    anticorps DOC2A, anticorps doc2-A, anticorps Doc2, anticorps double C2 domain alpha, anticorps double C2-like domains, alpha, anticorps double C2, alpha, anticorps DOC2A, anticorps doc2a, anticorps Doc2a
    Sujet

    Description: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,

    Aliases: DAB2, DOC-2

    Poids moléculaire
    82.4 kDa
    ID gène
    1601
    HGNC
    5899
    Pathways
    Synaptic Vesicle Exocytosis
Vous êtes ici:
Support technique