DOC2A anticorps (AA 652-749)
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- Antigène Voir toutes DOC2A Anticorps
- DOC2A (Double C2-Like Domains, alpha (DOC2A))
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Épitope
- AA 652-749
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DOC2A est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human DOC2 (AA: 652-749) expressed in E. coli.
- Clone
- 2H7C4
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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- Antigène
- DOC2A (Double C2-Like Domains, alpha (DOC2A))
- Autre désignation
- DOC2 (DOC2A Produits)
- Synonymes
- anticorps DOC2A, anticorps doc2-A, anticorps Doc2, anticorps double C2 domain alpha, anticorps double C2-like domains, alpha, anticorps double C2, alpha, anticorps DOC2A, anticorps doc2a, anticorps Doc2a
- Sujet
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Description: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,
Aliases: DAB2, DOC-2
- Poids moléculaire
- 82.4 kDa
- ID gène
- 1601
- HGNC
- 5899
- Pathways
- Synaptic Vesicle Exocytosis
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