Histone H3.3 anticorps

N° du produit ABIN5557308

Cet anticorps Lapin Monoclonal détecte spécifiquement Histone H3.3 dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Histone H3.3 anticorps (ABIN5557308)

Antigène: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Histone H3.3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 7B12

Détail du produit anti-Histone H3.3 anticorps

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Recombinant human Histone H3.3 protein, full length.

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Histone H3.3

Antigène: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Autre désignation: Histone H3.3

Sujet:

Synonyms: H3F3, H3.3A, Histone H3.3, H3F3A, PP781

Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

ID gène: 3020

UniProt: P84243