Fibronectin anticorps (AA 2240-2280)
Aperçu rapide pour Fibronectin anticorps (AA 2240-2280) (ABIN5557451)
Antigène
Voir toutes Fibronectin AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 2240-2280
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Purified by Protein G.
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Immunogène
- KLH conjugated synthetic peptide derived from human Fibronectin
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- Fibronectin
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Sujet
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Synonyms: Fibronectin, FN1, Cold-insoluble globulin, CIG
Background: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
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ID gène
- 2335
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UniProt
- P02751
Antigène
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