HDAC8 anticorps

N° du produit ABIN5557483

L’anticorps Lapin Monoclonal anti-HDAC8 a été validé pour WB, IF (cc) et IHC (p). Il convient pour détecter HDAC8 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HDAC8 anticorps (ABIN5557483)

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HDAC8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4C3

Détail du produit anti-HDAC8 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant human HDAC8 protein, around N-terminal 150aa.

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur HDAC8

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Autre désignation: HDAC8

Sujet:

Synonyms: HD8, WTS, RPD3, CDA07, CDLS5, MRXS6, HDACL1, Histone deacetylase 8, HDAC8

Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

ID gène: 55869

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process