SFMBT1 anticorps (C-Term)

N° du produit ABIN5563984

Cité dans 1 publication. Cet anticorps anti-SFMBT1 Polyclonal Lapin (ABIN5563984) détecte spécifiquement SFMBT1 dans WB, IP, ChIP, IF et ChIP-seq. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour SFMBT1 anticorps (C-Term) (ABIN5563984)

Antigène: SFMBT1 (Scm-Like with Four Mbt Domains 1 (SFMBT1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SFMBT1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), ChIP DNA-Sequencing (ChIP-seq)

Détail du produit anti-SFMBT1 anticorps

Épitope: C-Term

Fonction: SFMBT1 antibody (pAb)

Specificité: Mouse

Purification: Affinity Purified

Immunogène: This antibody was raised against a peptide within the C-terminal region of mouse SFMBT1.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2,500 dilution

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-SFMBT1 (ABIN5563984)

Zhang, Bonasio, Strino, Kluger, Holloway, Modzelewski, Cohen, Reinberg: "SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors." dans: Genes & development, Vol. 27, Issue 7, pp. 749-66, (2013) (PubMed).

Détails sur SFMBT1

Antigène: SFMBT1 (Scm-Like with Four Mbt Domains 1 (SFMBT1))

Autre désignation: SFMBT1

Sujet: SFMBT1 (Scm-Like With Four Mbt Domains 1) is a histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis.

Poids moléculaire: 110 kDa

NCBI Accession: NP_062333