Recombinant Netrin 1 anticorps

N° du produit ABIN5564235

L’anticorps Human Monoclonal anti-Netrin 1 a été validé pour ELISA et Func. Il convient pour détecter Netrin 1 dans des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant Netrin 1 anticorps (ABIN5564235)

Antigène: Netrin 1 (NTN1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Human

Clonalité: Monoclonal

Conjugué: Cet anticorp Netrin 1 est non-conjugé

Application: ELISA, Functional Studies (Func)

Clone: 2F5

Détail du produit anti-Netrin 1 anticorps

Specificité: Recognizes human and mouse Netrin-1.

Réactivité croisée: Humain, Souris

Aucune reactivité croisée: Souris

Réactivité croisée (Details): Does not recognize Netrin-4. Blocks human and mouse Netrin-1 activity on tumor cell lines in vitro and in vivo. Inhibits Netrin-1-enhanced infectivity of Hepatitis C Virus particles.

Pureté: >95 % (SDS-PAGE)

Immunogène: Recombinant human Netrin-1.

Isotype: IgG2

Information d'application

Commentaires:

anti-Netrin-1 (human), mAb (rec.) (blocking) (2F5) is composed of human variable regions (VH and VL) (lambda-chain) of immunoglobulin fused to the human lgG2 Fc domain.For negative control see Prod. No. AG-27B-0020PF.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 10 % glycerol.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur Netrin 1

Antigène: Netrin 1 (NTN1)

Autre désignation: Netrin-1

Sujet: Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b.

UniProt: O95631

Pathways: Regulation of Cell Size