Recombinant TNFSF4 (Oxelumab Biosimilar) anticorps
Aperçu rapide pour Recombinant TNFSF4 (Oxelumab Biosimilar) anticorps (ABIN5564244)
Antigène
Type d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- anti-OX40L (human), mAb (rec.) (blocking) (R4930) (preservative free)
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Specificité
- Recognizes human OX40L.
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Attributs du produit
- Recombinant Antibody. Recognizes human OX40L. Species cross-reactivity: Human. Clone: R4930. Isotype: Human IgG1kappa. Applications: FACS, FUNC, FUNC (Blocking). Host: CHO cells. Liquid. In PBS. OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.
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Pureté
- >95 % (SDS-PAGE)
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niveau d'endotoxine
- <0.001EU/μg
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Immunogène
- Recombinant human OX40L.
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Isotype
- IgG1 kappa
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Commentaires
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This antibody is a biosimilar generically called Oxelumab (CAS 1186098-83-8) and originally developed by Genentech. Oxelumab is a OX40 ligand blocker designed for the prevention of allergen-induced airway inflammation in adults with mild asthma. Potentially other application areas are transplantation and autoimmunity research or protection against inflammation-driven fibrosis.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- In PBS.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid freeze/thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C. Stable for at least 3 months after receipt when stored at +4°C.
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Date de péremption
- 12 months
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- TNFSF4 (Oxelumab Biosimilar)
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Classe de substances
- Biosimilar
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Sujet
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Alternate Names/Synonyms: CD252, CD134L, OX40 Ligand, TNFSF4, Tumor Necrosis Factor Superfamily Member 4, TAX Transcriptionally-activated Glycoprotein 1, TXGP1, gp34
Product Description: OX40L [CD252, CD134L] is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.
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UniProt
- P23510
Antigène
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