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Recombinant TNFSF4 (Oxelumab Biosimilar) anticorps

Reactivité: Humain FACS, Func Hôte: Human Monoclonal R4930 unconjugated Recombinant Antibody
N° du produit ABIN5564244
  • Antigène Tous les produits TNFSF4 (Oxelumab Biosimilar)
    TNFSF4 (Oxelumab Biosimilar)
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    Humain
    Hôte
    • 1
    • 1
    • 1
    Human
    Clonalité
    • 3
    Monoclonal
    Conjugué
    • 3
    Cet anticorp TNFSF4 (Oxelumab Biosimilar) est non-conjugé
    Application
    • 3
    • 2
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Specificité
    Recognizes human OX40L.
     Réactivité croisée
    Humain
    Pureté
    >95 % (SDS-PAGE)
    niveau d'endotoxine
    <0.001EU/μg
    Immunogène
    Recombinant human OX40L.
    Clone
    R4930
    Isotype
    IgG1
  • Commentaires

    This antibody is a biosimilar generically called Oxelumab (CAS 1186098-83-8) and originally developed by Genentech. Oxelumab is a OX40 ligand blocker designed for the prevention of allergen-induced airway inflammation in adults with mild asthma. Potentially other application areas are transplantation and autoimmunity research or protection against inflammation-driven fibrosis.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS.
    Agent conservateur
    Without preservative
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C. Stable for at least 3 months after receipt when stored at +4°C.
    Date de péremption
    12 months
  • Antigène
    TNFSF4 (Oxelumab Biosimilar)
    Abstract
    TNFSF4 (Oxelumab Biosimilar) Produits
    Synonymes
    anticorps CD134L, anticorps CD252, anticorps GP34, anticorps OX-40L, anticorps OX4OL, anticorps TXGP1, anticorps TNF superfamily member 4, anticorps TNFSF4
    Classe de substances
    Biosimilar
    Sujet
    OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.
    UniProt
    P23510
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