IL1F10 anticorps

N° du produit ABIN5564279

Cet anticorps Souris Monoclonal détecte spécifiquement IL1F10 dans ELISA et WB. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour IL1F10 anticorps (ABIN5564279)

Antigène: IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL1F10 est non-conjugé

Application: ELISA, Western Blotting (WB)

Clone: Nhat-1

Détail du produit anti-IL1F10 anticorps

Specificité: Recognizes human and mouse IL-38.

Réactivité croisée: Humain, Souris

Pureté: >95 % (SDS-PAGE)

Immunogène: Recombinant human IL-38.

Isotype: IgG2b

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur IL1F10

Antigène: IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))

Autre désignation: IL-38

Sujet: IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.