IL1F10 anticorps

N° du produit ABIN5564279

Cet anticorps Souris Monoclonal détecte spécifiquement IL1F10 dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour IL1F10 anticorps (ABIN5564279)

Antigène: IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL1F10 est non-conjugé

Application: ELISA, Western Blotting (WB)

Clone: Nhat-1

Détail du produit anti-IL1F10 anticorps

Specificité: Recognizes human and mouse IL-38.

Réactivité croisée: Humain, Souris

Pureté: >95 % (SDS-PAGE)

Immunogène: Recombinant human IL-38.

Isotype: IgG2b

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur IL1F10

Antigène: IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))

Autre désignation: IL-38

Sujet: IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.