C19ORF80 anticorps

N° du produit ABIN5564288

Cet anticorps Lapin Polyclonal détecte spécifiquement C19ORF80 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour C19ORF80 anticorps (ABIN5564288)

Antigène: C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C19ORF80 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-C19ORF80 anticorps

Fonction: anti-Betatrophin (human), pAb (IN108)

Specificité: Recognizes human betatrophin.

Attributs du produit: Polyclonal Antibody. Recognizes human ANGPTL8 [Betatrophin]. Source: Rabbit. Applications: ELISA, WB. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. ANGPTL8 (Angiopoietin-like protein 8, RIFL, Lipasin, Betatrophin) is a newly discovered secreted protein of 198 aa that was proposed to promote beta cell proliferation and improve glucose tolerance in mice. ANGPTL8 may also function in inhibition of lipase activity and on serum triglyceride regulation. ANGPTL8 is expressed in the liver and in white and brown adipose tissue of mice. In humans, ANGPTL8 is found to be predominantly expressed in the liver. ANGPTL8 levels are reduced by fasting and are elevated upon insulin resistance and during pregnancy. ANGPTL8, according to preliminary data could bind to the macrophage receptor Marco and also to RTN4R, a neuronal receptor. Recently, a study using ANGPTL8 KO mice showed that ANGPTL8 does not play a role in beta cell proliferation nor in glycemic control as previously thought, but regulates plasma triglyceride levels.

Immunogène: Recombinant human ANGPTL8 (betatrophin).

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Références pour anticorps anti-C19ORF80 (ABIN5564288)

Sun, Liu, Li, Tang, Zou, Chen, Zheng, Jiang, Shi: "Transplantation of betatrophin-expressing adipose-derived mesenchymal stem cells induces β-cell proliferation in diabetic mice." dans: International journal of molecular medicine, Vol. 39, Issue 4, pp. 936-948, (2017) (PubMed).

Détails sur C19ORF80

Antigène: C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))

Autre désignation: Betatrophin

Sujet:

Alternate Names/Synonyms: Angiopoietin-like Protein 8, ANGPTL8, Lipasin, Refeeding-induced Fat and Liver Protein, RIFL, Betatrophin

Product Description: ANGPTL8 (Angiopoietin-like protein 8, RIFL, Lipasin, Betatrophin) is a newly discovered secreted protein of 198 aa that was proposed to promote beta cell proliferation and improve glucose tolerance in mice. ANGPTL8 may also function in inhibition of lipase activity and on serum triglyceride regulation. ANGPTL8 is expressed in the liver and in white and brown adipose tissue of mice. In humans, ANGPTL8 is found to be predominantly expressed in the liver. ANGPTL8 levels are reduced by fasting and are elevated upon insulin resistance and during pregnancy. ANGPTL8, according to preliminary data could bind to the macrophage receptor Marco and also to RTN4R, a neuronal receptor. Recently, a study using ANGPTL8 KO mice showed that ANGPTL8 does not play a role in beta cell proliferation nor in glycemic control as previously thought, but regulates plasma triglyceride levels.