HDAC8 anticorps (N-Term)

N° du produit ABIN5596728

N° du produit (Fournisseur): 600-401-j72

L’anticorps Lapin Polyclonal anti-HDAC8 a été validé pour WB et ELISA. Il convient pour détecter HDAC8 dans des échantillons de Humain.

Aperçu rapide pour HDAC8 anticorps (N-Term) (ABIN5596728)

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC8 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HDAC8 anticorps

Épitope: N-Term

N° du produit (Fournisseur): 600-401-j72

Fournisseur: Rockland

Fonction: HDAC8 (near N-terminus) Antibody

Réactivité croisée (Details): A BLAST analysis was used to suggest cross-reactivity with rat, mouse, human, and bovine based on 100 % sequence homology.

Attributs du produit: Synonyms: rabbit anti-HDAC-8 antibody, HDAC8, HDAC 8, HD-8, HD 8, Histone deacetylase 8, Histone deacetylase-8, HD8, HDACL1, CDA07

Purification: Anti-HDAC8 was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Stérilité: Sterile filtered

Immunogène:

Immunogen: Anti-HDAC8 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide near the N-terminus of human HDAC8 protein.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: Anti-HDAC8 antibody has been tested by ELISA, and western blot and is useful for Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~41 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1: 10,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 30 % Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur HDAC8

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Autre désignation: HDAC8

Sujet: Background: HDAC8 is located in the nucleus and cytoplasm, expressed weakly in most tissues with higher expression in the heart, brain, kidney, pancreas, liver, lunch, placenta, prostate, and kidney. It is responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). The result of deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Anti-HDAC8 therefore is ideal for investigators interested in Stem Cells , Cardiovascular , or Epigenetics and Nuclear Signaling research.

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process