Metabotropic Glutamate Receptor 6 anticorps (AA 480-585)

N° du produit ABIN5611180

Détail du produit anti-Metabotropic Glutamate Receptor 6 anticorps

Antigène: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Épitope: AA 480-585

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human GRM6 (AA: extra 480-585) expressed in E. coli.

Clone: 7D9C9

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur Metabotropic Glutamate Receptor 6

Antigène: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Autre désignation: GRM6 (GRM6 Produits)

Synonymes: anticorps mGluR6, anticorps CSNB1B, anticorps GPRC1F, anticorps MGLUR6, anticorps mGlu6, anticorps GRM6, anticorps BC021919, anticorps Gm3, anticorps Gprc1f, anticorps nerg1, anticorps nob2, anticorps nob3, anticorps nob4, anticorps si:dkey-52h10.3, anticorps cb496, anticorps grma, anticorps zK13A21.16, anticorps zgc:158329, anticorps glutamate metabotropic receptor 6, anticorps glutamate receptor, metabotropic 6, anticorps glutamate receptor, metabotropic 6a, anticorps glutamate receptor, metabotropic 6b, anticorps Grm6, anticorps GRM6, anticorps grm6a, anticorps grm6b

Sujet:

Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Aliases: mGlu6, CSNB1B, GPRC1F, MGLUR6

Poids moléculaire: 95.5 kDa

ID gène: 2916

HGNC: 2916