CCR7 anticorps

N° du produit ABIN5611258

Détail du produit anti-CCR7 anticorps

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCR7 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human CD197 (AA: extra mix) expressed in E. coli.

Clone: 4B7B8

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur CCR7

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Autre désignation: CD197 (CCR7 Produits)

Synonymes: anticorps zgc:165629, anticorps ccr7-a, anticorps CD197, anticorps Cdw197, anticorps Cmkbr7, anticorps EBI1, anticorps Ebi1h, anticorps BLR2, anticorps CDw197, anticorps CMKBR7, anticorps chemokine (C-C motif) receptor 7, anticorps C-C motif chemokine receptor 7, anticorps C-C motif chemokine receptor 7 L homeolog, anticorps ccr7, anticorps CCR7, anticorps ccr7.L, anticorps Ccr7

Sujet:

Description: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.

Aliases: BLR2, EBI1, CCR-7, CCR7, CDw197, CMKBR7, CC-CKR-7

Poids moléculaire: 42.9 kDa

ID gène: 1236

HGNC: 1236

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process