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CTLA4 anticorps (AA 36-161)

CTLA4 Reactivité: Humain FACS, WB, ELISA, IHC, ICC, Neut Hôte: Souris Monoclonal 8B3F8 unconjugated
N° du produit ABIN5611264
  • Antigène Voir toutes CTLA4 Anticorps
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Épitope
    • 16
    • 11
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 36-161
    Reactivité
    • 95
    • 67
    • 35
    • 5
    • 4
    Humain
    Hôte
    • 62
    • 51
    • 18
    • 12
    • 1
    • 1
    Souris
    Clonalité
    • 88
    • 54
    • 2
    Monoclonal
    Conjugué
    • 67
    • 17
    • 13
    • 12
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CTLA4 est non-conjugé
    Application
    • 86
    • 65
    • 51
    • 34
    • 19
    • 17
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human CD152 (AA: extra 36-161) expressed in E. coli.
    Clone
    8B3F8
    Isotype
    IgG1
    Top Product
    Discover our top product CTLA4 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
    Autre désignation
    CD152 (CTLA4 Produits)
    Synonymes
    anticorps CTLA-4, anticorps CTLA4, anticorps CD152, anticorps Cd152, anticorps Ctla-4, anticorps Ly-56, anticorps CD, anticorps CELIAC3, anticorps GRD4, anticorps GSE, anticorps IDDM12, anticorps sCTLA4, anticorps cytotoxic T-lymphocyte associated protein 4, anticorps cytotoxic T-lymphocyte-associated protein 4, anticorps CTLA4, anticorps Ctla4
    Sujet

    Description: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

    Aliases: CTLA4, CD, GSE, GRD4, ALPS5, CTLA-4, IDDM12, CELIAC3

    Poids moléculaire
    24.6 kDa
    ID gène
    1493
    HGNC
    1493
    Pathways
    Cancer Immune Checkpoints
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