CD276 anticorps (AA 29-466)

N° du produit ABIN5611271

Cet anticorps Souris Monoclonal détecte spécifiquement CD276 dans ELISA, FACS, IHC et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour CD276 anticorps (AA 29-466) (ABIN5611271)

Antigène: CD276

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD276 est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: 8C1C2

Détail du produit anti-CD276 anticorps

Épitope: AA 29-466

Fonction: B7H3 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human B7H3 (AA: 29-466) expressed in HEK293 cells.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/100 - 1/500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur CD276

Antigène: CD276

Autre désignation: B7H3

Sujet: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 57.2 kDa

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints