CHRNA4 anticorps (AA 29-242)

N° du produit ABIN5611309

Cet anticorps anti-CHRNA4 est un anticorps Souris Monoclonal détectant CHRNA4 dans ELISA. Adapté pour Humain.

Aperçu rapide pour CHRNA4 anticorps (AA 29-242) (ABIN5611309)

Antigène: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CHRNA4 est non-conjugé

Application: ELISA

Clone: 7B4H1

Détail du produit anti-CHRNA4 anticorps

Épitope: AA 29-242

Fonction: CHRNA4 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CHRNA4 (AA: 29-242) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur CHRNA4

Antigène: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Autre désignation: CHRNA4

Sujet: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 70 kDa

ID gène: 1137

UniProt: P43681

Pathways: Synaptic Membrane