CXCR3 anticorps
Aperçu rapide pour CXCR3 anticorps (ABIN5611329)
Antigène
Voir toutes CXCR3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- CD183 Antibody
-
Purification
- Purified antibody
-
Immunogène
- Purified recombinant fragment of human CD183 (AA: mix) expressed in E. Coli.
-
Isotype
- IgG1
-
-
-
-
Indications d'application
-
ELISA: 1/10000
FCM: 1/200 - 1/400
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
-
Autre désignation
- CD183
-
Sujet
-
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).
-
Poids moléculaire
- 40.7 kDa
-
ID gène
- 2833
Antigène
-