CD207 anticorps (AA 155-328)
Aperçu rapide pour CD207 anticorps (AA 155-328) (ABIN5611331)
Antigène
Voir toutes CD207 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 155-328
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Fonction
- CD207 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human CD207 (AA: 155-328) expressed in E. Coli.
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Isotype
- IgG2b
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- CD207 (CD207 Molecule, Langerin (CD207))
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Autre désignation
- CD207
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Sujet
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The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
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Poids moléculaire
- 36.7 kDa
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UniProt
- Q9UJ71
Antigène
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