CHRND anticorps (AA 22-245)
Aperçu rapide pour CHRND anticorps (AA 22-245) (ABIN5611361)
Antigène
Voir toutes CHRND AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 22-245
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Fonction
- CHRND Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human CHRND (AA: 22-245) expressed in E. Coli.
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Isotype
- IgG1
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))
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Autre désignation
- CHRND
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Sujet
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The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.
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Poids moléculaire
- 58.8 kDa
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ID gène
- 1144
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UniProt
- Q07001
Antigène
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