Glycogenin 1 anticorps (AA 1-73)

N° du produit ABIN561206

L’anticorps Souris Monoclonal anti-Glycogenin 1 a été validé pour WB, ELISA et IHC (p). Il convient pour détecter Glycogenin 1 dans des échantillons de Humain. Il y a 6+ publications disponibles.

Aperçu rapide pour Glycogenin 1 anticorps (AA 1-73) (ABIN561206)

Antigène: Glycogenin 1 (GYG1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Glycogenin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3B5

Détail du produit anti-Glycogenin 1 anticorps

Épitope: AA 1-73

Fonction: Mouse monoclonal antibody raised against a partial recombinant GYG1.

Séquence: MTDQAFVTLT TNDAYAKGAL VLGSSLKQHR TTRRLVVLAT PQVSDSMRKV LETVFDEVIM VDVLDSGDSA HLT

Réactivité croisée: Humain, Rat

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: GYG1 (NP_004121, 1 a.a. ~ 73 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-Glycogenin 1 (ABIN561206)

Tasca, Fattori, Monforte, Hedberg-Oldfors, Sabatelli, Udd, Boldrini, Bertini, Ricci, Oldfors: "Start codon mutation of GYG1 causing late-onset polyglucosan body myopathy with nemaline rods." dans: Journal of neurology, Vol. 263, Issue 10, pp. 2133-5, (2016) (PubMed).

Hedberg-Oldfors, Glamuzina, Ruygrok, Anderson, Elliott, Watkinson, Occleshaw, Abernathy, Turner, Kingston, Murphy, Oldfors: "Cardiomyopathy as presenting sign of glycogenin-1 deficiency-report of three cases and review of the literature." dans: Journal of inherited metabolic disease, Vol. 40, Issue 1, pp. 139-149, (2016) (PubMed).

Nilsson, Halim, Larsson, Moslemi, Oldfors, Larson, Nilsson: "LC-MS/MS characterization of combined glycogenin-1 and glycogenin-2 enzymatic activities reveals their self-glucosylation preferences." dans: Biochimica et biophysica acta, Vol. 1844, Issue 2, pp. 398-405, (2014) (PubMed).

Malfatti, Nilsson, Hedberg-Oldfors, Hernandez-Lain, Michel, Dominguez-Gonzalez, Viennet, Akman, Kornblum, Van den Bergh, Romero, Engel, DiMauro, Oldfors: "A new muscle glycogen storage disease associated with glycogenin-1 deficiency." dans: Annals of neurology, Vol. 76, Issue 6, pp. 891-8, (2014) (PubMed).

Taylor, Meyers, Phipps, Kishnani, Cheng, Scheule, Moreland: "Dysregulation of multiple facets of glycogen metabolism in a murine model of Pompe disease." dans: PLoS ONE, Vol. 8, Issue 2, pp. e56181, (2013) (PubMed).

Nilsson, Halim, Moslemi, Pedersen, Nilsson, Larson, Oldfors: "Molecular pathogenesis of a new glycogenosis caused by a glycogenin-1 mutation." dans: Biochimica et biophysica acta, Vol. 1822, Issue 4, pp. 493-9, (2012) (PubMed).

Détails sur Glycogenin 1

Antigène: Glycogenin 1 (GYG1)

Autre désignation: GYG1

Sujet: Full Gene Name: glycogenin 1
Synonyms: GYG

ID gène: 2992

NCBI Accession: NM_004130

Pathways: Cellular Glucan Metabolic Process