HSD17B1 anticorps (AA 189-285)

N° du produit ABIN561371

Il existe 3+ publications pour ce produit. L’anticorps anti-HSD17B1 Monoclonal Souris est utilisé pour la détection de HSD17B1 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC (p).

Aperçu rapide pour HSD17B1 anticorps (AA 189-285) (ABIN561371)

Antigène: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSD17B1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2E5

Détail du produit anti-HSD17B1 anticorps

Épitope: AA 189-285

Fonction: Mouse monoclonal antibody raised against a partial recombinant HSD17B1.

Séquence: VHTAFMEKVL GSPEEVLDRT DIHTFHRFYQ YLAHSKQVFR EAAQNPEEVA EVFLTALRAP KPTLRYFTTE RFLPLLRMRL DDPSGSNYVT AMHREVF

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: HSD17B1 (NP_000404, 189 a.a. ~ 285 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-HSD17B1 (ABIN561371)

McNamara, Oguro, Omata, Kikuchi, Guestini, Suzuki, Yang, Abe, Hirakawa, Brown, Takanori, Ohuchi, Sasano: "The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer." dans: Breast cancer research and treatment, Vol. 161, Issue 2, pp. 213-227, (2016) (PubMed).

Inoue, Miki, Abe, Hatori, Hosaka, Kariya, Kakuo, Fujimura, Hachiya, Aiba, Sasano: "The role of estrogen-metabolizing enzymes and estrogen receptors in human epidermis." dans: Molecular and cellular endocrinology, Vol. 344, Issue 1-2, pp. 35-40, (2011) (PubMed).

Chanplakorn, Chanplakorn, Suzuki, Ono, Chan, Miki, Saji, Ueno, Toi, Sasano: "Increased estrogen sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type 1(17beta-HSD1) following neoadjuvant aromatase inhibitor therapy in breast cancer patients." dans: Breast cancer research and treatment, Vol. 120, Issue 3, pp. 639-48, (2010) (PubMed).

Détails sur HSD17B1

Antigène: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Autre désignation: HSD17B1

Sujet: Full Gene Name: hydroxysteroid (17-beta) dehydrogenase 1
Synonyms: EDH17B2,EDHB17,HSD17,MGC138140,SDR28C1

ID gène: 3292

NCBI Accession: NM_000413

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis