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Topoisomerase I anticorps (AA 692-765)

TOP1 Reactivité: Humain WB, ELISA, IHC (p) Hôte: Souris Monoclonal 1A1 unconjugated
N° du produit ABIN563222
  • Antigène Voir toutes Topoisomerase I (TOP1) Anticorps
    Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
    Épitope
    • 11
    • 11
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 692-765
    Reactivité
    • 66
    • 25
    • 14
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 10
    • 2
    Souris
    Clonalité
    • 44
    • 22
    Monoclonal
    Conjugué
    • 36
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Topoisomerase I est non-conjugé
    Application
    • 42
    • 20
    • 19
    • 14
    • 9
    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Mouse monoclonal antibody raised against a partial recombinant TOP1.
    Séquence
    QRLEEQLMKL EVQATDREEN KQIALGTSKL NYLDPRITVA WCKKWGVPIE KIYNKTQREK FAWAIDMADE DYEF
     Réactivité croisée
    Humain
    Attributs du produit
    Antibody Reactive Against Recombinant Protein.
    Immunogène
    TOP1 (NP_003277, 692 a.a. ~ 765 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    1A1
    Isotype
    IgG1
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Kobayashi, Aida, Nagaoka, Begum, Kitawaki, Nakata, Stanlie, Doi, Kato, Okazaki, Shinkura, Muramatsu, Kinoshita, Honjo: "AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 52, pp. 22375-80, (2010) (PubMed).

  • Antigène
    Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
    Autre désignation
    TOP1 (TOP1 Produits)
    Synonymes
    anticorps CG6146, anticorps Dmel\\CG6146, anticorps TOP1, anticorps TopI, anticorps Topo I, anticorps TopoI, anticorps dTopoI, anticorps l(1)G0134, anticorps l(1)G0201, anticorps l(1)G0229, anticorps l(1)G0278, anticorps l(1)top1, anticorps top1, anticorps topo I, anticorps topoI, anticorps DNA topoisomerase 1 beta, anticorps DNA topoisomerase I alpha, anticorps MGO1, anticorps MGOUN 1, anticorps MTE17.1, anticorps MTE17_1, anticorps TOP1BETA, anticorps TOPOISOMERASE 1, anticorps TOPI, anticorps AI467334, anticorps D130064I21Rik, anticorps Top-1, anticorps Ab2-086, anticorps topi, anticorps Topoisomerase 1, anticorps DNA topoisomerase I, anticorps DNA topoisomerase I alpha, anticorps DNA topoisomerase 1, anticorps topoisomerase (DNA) I, anticorps DNA topoisomerase I, gene 1 L homeolog, anticorps Top1, anticorps top1, anticorps topA, anticorps ZMO1193, anticorps MRAD2831_RS63095, anticorps Lferr_0016, anticorps PC1_2015, anticorps Za10_0136, anticorps Gbro_0575, anticorps Dd586_2108, anticorps Kvar_3044, anticorps Alvin_2069, anticorps Dacet_0849, anticorps Mrub_1615, anticorps Arnit_2962, anticorps Ndas_4953, anticorps Trad_2377, anticorps Acear_1653, anticorps Mahau_0844, anticorps Mesop_4109, anticorps Thein_1586, anticorps Theth_0241, anticorps TOP1ALPHA, anticorps top-1, anticorps TOP1, anticorps top1.1.L
    Classe de substances
    Viral Protein
    Sujet
    Full Gene Name: topoisomerase (DNA) I
    Synonyms: TOPI
    ID gène
    7150
    NCBI Accession
    NM_003286
    Pathways
    Caspase Cascade in Apoptosis, Stem Cell Maintenance
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