Topoisomerase I anticorps (AA 692-765)
Aperçu rapide pour Topoisomerase I anticorps (AA 692-765) (ABIN563222)
Antigène
Voir toutes Topoisomerase I (TOP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 692-765
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Fonction
- Mouse monoclonal antibody raised against a partial recombinant TOP1.
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Séquence
- QRLEEQLMKL EVQATDREEN KQIALGTSKL NYLDPRITVA WCKKWGVPIE KIYNKTQREK FAWAIDMADE DYEF
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Réactivité croisée
- Humain
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Attributs du produit
- Antibody Reactive Against Recombinant Protein.
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Immunogène
- TOP1 (NP_003277, 692 a.a. ~ 765 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- In 1x PBS, pH 7.4
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Conseil sur la manipulation
- Aliquot to avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 52, pp. 22375-80, (2010) (PubMed).
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- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
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Autre désignation
- TOP1
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Sujet
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Full Gene Name: topoisomerase (DNA) I
Synonyms: TOPI -
ID gène
- 7150
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NCBI Accession
- NM_003286
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Pathways
- Caspase Cascade in Apoptosis, Stem Cell Maintenance
Antigène
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