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R-RAS2 anticorps (PE)

Cet anticorps anti- est un anticorps Souris Monoclonal détectant dans ICFC. Adapté pour Humain.
N° du produit ABIN5633276

Aperçu rapide pour R-RAS2 anticorps (PE) (ABIN5633276)

Antigène

R-RAS2

Reactivité

Humain

Hôte

  • 1
Souris

Clonalité

  • 1
Monoclonal

Conjugué

  • 1
PE

Application

  • 1
  • 1
  • 1
  • 1
Intracellular Flow Cytometry (ICFC)

Clone

EM-50
  • Fonction

    Anti-R-RAS2 PE

    Specificité

    The mouse monoclonal antibody EM-50 recognizes R-Ras2 / TC21 protein (intracellular antigen) and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras.

    Réactivité croisée (Details)

    Human

    Purification

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogène

    Human TC21

    Isotype

    IgG1 kappa
  • Indications d'application

    Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.

    Restrictions

    For Research Use only
  • Concentration

    0.1 mg/mL

    Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène

    R-RAS2

    Sujet

    RAS related 2,R-Ras2 / TC21 is the only member of R-Ras family of small GTPases that shows transforming activities similar to H-Ras, N-Ras, and K-Ras, and it is also structurally similar to them. R-Ras2 seems to play an important role in activating signal transduction pathways that control cell proliferation. Its mutations are associated with the growth of certain tumors, but also overexpression of the wild type form of R-Ras2 has been frequently detected in various carcinomas. Pseudogenes of R-Ras2 gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.,TC21, RRAS2

    ID gène

    22800

    UniProt

    P62070
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