USP9X anticorps (AA 1-90)

N° du produit ABIN563570

Il existe 6+ publications pour ce produit. L’anticorps anti-USP9X Monoclonal Souris est utilisé pour la détection de USP9X dans des échantillons de Humain. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour USP9X anticorps (AA 1-90) (ABIN563570)

Antigène: USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp USP9X est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 1C4

Détail du produit anti-USP9X anticorps

Épitope: AA 1-90

Fonction: Mouse monoclonal antibody raised against a partial recombinant USP9X.

Séquence: MTATTRGSPV GGNDNQGQAP DGQSQPPLQQ NQTSSPDSSN ENSPATPPDE QGQGDAPPQL EDEEPAFPHT DLAKLDDMIN RPRWVVPVLP

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: USP9X (NP_068706, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-USP9X (ABIN563570)

Kim, Kim, Park, Lee, Lim: "Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition." dans: EMBO reports, Vol. 17, Issue 1, pp. 64-78, (2016) (PubMed).

Wolfsperger, Hogh-Binder, Schittenhelm, Psaras, Ritter, Bornes, Huber, Jendrossek, Rudner: "Deubiquitylating enzyme USP9x regulates radiosensitivity in glioblastoma cells by Mcl-1-dependent and -independent mechanisms." dans: Cell death & disease, Vol. 7, pp. e2039, (2016) (PubMed).

Wang, Xie, Li, Owonikoko, Ramalingam, Khuri, Curran, Wang, Deng: "Role of Ku70 in deubiquitination of Mcl-1 and suppression of apoptosis." dans: Cell death and differentiation, Vol. 21, Issue 7, pp. 1160-9, (2014) (PubMed).

Mazumder, Choudhary, Al-Harbi, Almasan: "Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells." dans: Cancer research, Vol. 72, Issue 12, pp. 3069-79, (2012) (PubMed).

Trivigno, Essmann, Huber, Rudner: "Deubiquitinase USP9x confers radioresistance through stabilization of Mcl-1." dans: Neoplasia (New York, N.Y.), Vol. 14, Issue 10, pp. 893-904, (2012) (PubMed).

Hikita, Takehara, Shimizu, Kodama, Shigekawa, Iwase, Hosui, Miyagi, Tatsumi, Ishida, Li, Kanto, Hiramatsu, Hayashi: "The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib." dans: Hepatology (Baltimore, Md.), Vol. 52, Issue 4, pp. 1310-21, (2010) (PubMed).

Détails sur USP9X

Antigène: USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))

Autre désignation: USP9X

Sujet: Full Gene Name: ubiquitin specific peptidase 9, X-linked
Synonyms: DFFRX,FAF,FAM

ID gène: 8239

NCBI Accession: NM_021906