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USP15 anticorps (AA 1-235)

Cet anticorps anti-USP15 est un anticorps Souris Monoclonal détectant USP15 dans WB, ELISA et IF. Adapté pour Humain. Ce Primary Antibody a été cité dans 9+ publications.
N° du produit ABIN564282

Aperçu rapide pour USP15 anticorps (AA 1-235) (ABIN564282)

Antigène

Voir toutes USP15 Anticorps
USP15 (Ubiquitin Specific Peptidase 15 (USP15))

Reactivité

  • 47
  • 27
  • 9
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 43
  • 3
  • 1
Souris

Clonalité

  • 43
  • 3
Monoclonal

Conjugué

  • 27
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp USP15 est non-conjugé

Application

  • 36
  • 24
  • 11
  • 9
  • 4
  • 4
  • 4
  • 2
Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone

1C10
  • Épitope

    • 8
    • 7
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-235

    Fonction

    Mouse monoclonal antibody raised against a full length recombinant USP15.

    Séquence

    MAEGGAADLD TQRSDIATLL KTSLRKGDTW YLVDSRWFKQ WKKYVGFDSW DKYQMGDQNV YPGPIDNSGL LKDGDAQSLK EHLIDELDYI LLPTEGWNKL VSWYTLMEGQ EPIARKVVEQ GMFVKHCKVE VYLTELKLCE NGNMNNVVTR RFSKADTIDT IEKEIRKIFS IPDEKETRLW NKYMSNTFEP LNKPDSTIQD AGLYQGQVLV IEQKNEDGTW PRGPSTPKKP LEQSC

     Réactivité croisée

    Humain

    Attributs du produit

    Antibody Reactive Against Recombinant Protein.

    Immunogène

    USP15 (AAH20688, 1 a.a. ~ 235 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Isotype

    IgG1
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    In 1x PBS, pH 7.4

    Conseil sur la manipulation

    Aliquot to avoid repeated freezing and thawing.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Pauli, Chan, Davis, Gableske, Wang, Feister, Gack: "The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25." dans: Science signaling, Vol. 7, Issue 307, pp. ra3, (2014) (PubMed).

    García-Caballero, Gadotti, Stemkowski, Weiss, Souza, Hodgkinson, Bladen, Chen, Hamid, Pizzoccaro, Deage, François, Bourinet, Zamponi: "The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity." dans: Neuron, Vol. 83, Issue 5, pp. 1144-58, (2014) (PubMed).

    Cornelissen, Haddad, Wauters, Van Humbeeck, Mandemakers, Koentjoro, Sue, Gevaert, De Strooper, Verstreken, Vandenberghe: "The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy." dans: Human molecular genetics, Vol. 23, Issue 19, pp. 5227-42, (2014) (PubMed).

    Fernandez-Sanchez, Sechet, Margottin-Goguet, Rogge, Bianchi: "The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation." dans: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17390-7, (2010) (PubMed).

    Vos, Altreuter, White, Howley: "The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability." dans: Journal of virology, Vol. 83, Issue 17, pp. 8885-92, (2009) (PubMed).

    Xu, Takanashi, Oikawa, Tanaka, Nishi, Isaka, Kudo, Kuroda: "USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis." dans: Biochemical and biophysical research communications, Vol. 388, Issue 2, pp. 366-71, (2009) (PubMed).

    Cayli, Klug, Chapiro, Fröhlich, Krasteva, Orel, Meinhardt: "COP9 signalosome interacts ATP-dependently with p97/valosin-containing protein (VCP) and controls the ubiquitination status of proteins bound to p97/VCP." dans: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34944-53, (2009) (PubMed).

    Miyauchi, Kato, Tokunaga, Iwai: "The COP9/signalosome increases the efficiency of von Hippel-Lindau protein ubiquitin ligase-mediated hypoxia-inducible factor-alpha ubiquitination." dans: The Journal of biological chemistry, Vol. 283, Issue 24, pp. 16622-31, (2008) (PubMed).

    Schweitzer, Bozko, Dubiel, Naumann: "CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha." dans: The EMBO journal, Vol. 26, Issue 6, pp. 1532-41, (2007) (PubMed).

  • Antigène

    USP15 (Ubiquitin Specific Peptidase 15 (USP15))

    Autre désignation

    USP15

    Sujet

    Full Gene Name: ubiquitin specific peptidase 15
    Synonyms: KIAA0529,MGC131982,MGC149838,MGC74854,UNPH4

    ID gène

    9958
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