AIRE anticorps

N° du produit ABIN5647007

Cet anticorps anti-AIRE est un anticorps Polyclonal produit chez le Lapin, détectant AIRE dans WB et FACS. Convient pour Humain et Rat.

Aperçu rapide pour AIRE anticorps (ABIN5647007)

Antigène: AIRE (Autoimmune Regulator (AIRE))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIRE est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-AIRE anticorps

Purification: Antigen affinity purified

Immunogène: Amino acids M1-K120 from the human protein were used as the immunogen for the AIRE antibody.

Isotype: IgG

Information d'application

Indications d'application: Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: Prior to reconstitution, store at 4°C. After reconstitution, the AIRE antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur AIRE

Antigène: AIRE (Autoimmune Regulator (AIRE))

Autre désignation: AIRE

Sujet: The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

UniProt: O43918

Pathways: Chromatin Binding