Calpastatin anticorps (AA 275-310)
Aperçu rapide pour Calpastatin anticorps (AA 275-310) (ABIN5647087)
Antigène
Voir toutes Calpastatin (CAST) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 275-310
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Fonction
- Calpastatin Antibody
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Purification
- Antigen affinity
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Immunogène
- Amino acids 275-310 (QEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLR-human) were used as the immunogen for the Calpastatin antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Calpastatin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Calpastatin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Calpastatin (CAST)
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Autre désignation
- Calpastatin
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Sujet
- Calpastatin is a protein that in humans is encoded by the CAST gene. It is mapped to 5q15. The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
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ID gène
- 831
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UniProt
- P20810
Antigène
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