Calpastatin anticorps (AA 275-310)

N° du produit ABIN5647087

Détail du produit anti-Calpastatin anticorps

Antigène: Calpastatin (CAST)

Épitope: AA 275-310

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calpastatin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: Antigen affinity purified

Immunogène: Amino acids 275-310 (QEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLR-human) were used as the immunogen for the Calpastatin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Calpastatin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells,Immunohistochemistry (FFPE): 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Calpastatin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Calpastatin

Antigène: Calpastatin (CAST)

Autre désignation: Calpastatin (CAST Produits)

Synonymes: anticorps BS-17, anticorps calp3, anticorps CAST, anticorps sb:cb966, anticorps zgc:194249, anticorps cast, anticorps DKFZp469E0716, anticorps calpastatin, anticorps calpastatin S homeolog, anticorps Calpastatin, anticorps CAST, anticorps Cast, anticorps cast.S, anticorps cast, anticorps VDBG_09182, anticorps ical

Sujet: Calpastatin is a protein that in humans is encoded by the CAST gene. It is mapped to 5q15. The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

UniProt: P20810