IL17F anticorps (AA 29-161)
Aperçu rapide pour IL17F anticorps (AA 29-161) (ABIN5647177)
Antigène
Voir toutes IL17F AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 29-161
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Fonction
- IL17F Antibody / Interleukin 17F
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Purification
- Antigen affinity
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Immunogène
- A recombinant mouse protein corresponding to amino acids R29-A161 was used as the immunogen for the IL17F antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the IL17F antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the IL17F antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IL17F (Interleukin 17F (IL17F))
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Autre désignation
- IL17F
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Sujet
- Interleukin 17F, also called IL17F is involved in the regulation of normal versus aberrant T-cell responses. This gene is mapped to 6p12.2. The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. It is suggested that targeting IL17 and IL17F or antagonizing IL17R might mitigate neutrophil-mediated inflammation in CF.
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UniProt
- Q7TNI7
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
Antigène
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