MXD1 anticorps

N° du produit ABIN5647191

Cet anticorps Lapin Polyclonal détecte spécifiquement MXD1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour MXD1 anticorps (ABIN5647191)

Antigène: MXD1 (MAX Dimerization Protein 1 (MXD1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MXD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MXD1 anticorps

Réactivité croisée (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogène: A recombinant human protein corresponding to amino acids M1-L221 was used as the immunogen for the MAD antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MAD antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the MAD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur MXD1

Antigène: MXD1 (MAX Dimerization Protein 1 (MXD1))

Autre désignation: MAD / MXD1 / Max dimerization protein 1

Sujet: MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UniProt: Q05195