Muscarinic Acetylcholine Receptor M2 anticorps (AA 352-376)
Aperçu rapide pour Muscarinic Acetylcholine Receptor M2 anticorps (AA 352-376) (ABIN5647209)
Antigène
Voir toutes Muscarinic Acetylcholine Receptor M2 (CHRM2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 352-376
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Réactivité croisée (Details)
- Expected species reactivity: Human
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Purification
- Antigen affinity purified
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Immunogène
- Amino acids 352-376 (QNGDEKQNIVARKIVKMTKQPAKKK) from the human protein were used as the immunogen for the CHRM2 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the CHRM2 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- -20 °C
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Stockage commentaire
- After reconstitution, the CHRM2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))
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Autre désignation
- CHRM2
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Sujet
- The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
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UniProt
- P08172
Antigène
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