PON1 anticorps

N° du produit ABIN5647230

Cet anticorps Lapin Polyclonal détecte spécifiquement PON1 dans WB, IHC (p) et ELISA (Capture). Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour PON1 anticorps (ABIN5647230)

Antigène: PON1 (Paraoxonase 1 (PON1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PON1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Capture)

Détail du produit anti-PON1 anticorps

Purification: Antigen affinity purified

Immunogène: A recombinant mouse protein corresponding to amino acids A30-D274 was used as the immunogen for the PON1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PON1 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,ELISA (Capture, mouse recombinant protein): 0.1-0.5 μg/mL (BSA-free format available)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the PON1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur PON1

Antigène: PON1 (Paraoxonase 1 (PON1))

Autre désignation: PON1

Sujet: Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-?, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.

UniProt: P52430