Thymic Stromal Lymphopoietin anticorps
Aperçu rapide pour Thymic Stromal Lymphopoietin anticorps (ABIN5647286)
Antigène
Voir toutes Thymic Stromal Lymphopoietin (TSLP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- TSLP Antibody / Thymic stromal lymphopoietin
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Séquence
- KVTTNKCLEQ VSQLQGLWRR FNRPLLKQQ
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Purification
- Antigen affinity
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Immunogène
- Amino acids KVTTNKCLEQVSQLQGLWRRFNRPLLKQQ were used as the immunogen for the TSLP antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the TSLP antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the TSLP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Thymic Stromal Lymphopoietin (TSLP)
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Autre désignation
- TSLP
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Sujet
- Thymic stromal lymphopoietin, also called TSLP is a protein belonging to the cytokine family. This gene is mapped to 5q22.1. It encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2(TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases.
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UniProt
- Q969D9
Antigène
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