TTN
Reactivité: Rat, Souris
IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC (FFPE): 1:25
Restrictions
For Research Use only
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the Titin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Antigène
Titin (TTN)
Autre désignation
Titin / TTN
Sujet
Titin is a key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.